Propionibacterium acnes

Whenever a pore is blocked, this anaerobic bacterium overgrows and secretes chemical substances that break down the wall from the pore and forming an Propionibacterium acnes lesion (folliculitis), probably spilling bacteria including Staphylococcus aureus in to the damaged pores and skin. Preliminary analysis exhibits wholesome pores are only colonized by P.acnes even though unhealthy ones universally incorporate the non-pore-resident Staphylococcus epidermidis, among other bacterial contaminants. No matter if this is often a root causality, just opportunistic & a side-effect, or a more complex pathological duality between P.Propionibacterium acnes and this particular Staph is not known.[1] P.acnes has also been found in corneal ulcers and is often a common cause of chronic endophthalmitis following cataract surgery. Rarely, it infects heart valves leading to endocarditis, and infections of joints (septic arthritis) have been reported. Furthermore, Propionibacterium have been found in ventriculostomy insertion sites, and areas subcutaneous to suture sites in patients that have undergone craniotomy. Propionibacterium acnes is often found in bronchoalveolar lavage of approximately 70% patients with sarcoidosis and is associated with illness activity, however it is often also found in 23% of controls.[2][3] The sub-species of P.acnes that cause these infections of otherwise sterile tissues (prior to medical procedures), however, are the same sub-species that are found on the pores and skin of individuals that do not have acne-prone pores and skin and thus are likely local contaminants. Moderate to severe Acne vulgaris appears to be more normally associated with virulent sub-strains.

Incoming search terms for the article:

• propionibacterium acnes areas subcutaneous to suture sites in patients that have undergone craniotomy
• propionibacterium folliculitis